产品名称
DPOA2 Rabbit Polyclonal Antibody
蛋白名称
DNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q14181
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q14181/entry
Mouse Swissprot No.
P33611
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P33611
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941O89043
免疫原
Synthesized peptide derived from part region of human protein
特异性
DPOA2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
domain:The N-terminal 240 amino acids are sufficient to mediate complex formation.,function:May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery.,PTM:Phosphorylated in a cell cycle-dependent manner, in G2/M phase.,similarity:Belongs to the DNA polymerase alpha subunit B family.,subunit:DNA polymerase alpha:primase is a four subunit enzyme complex, which is assembled throughout the cell cycle, and consists of the two DNA polymerase subunits A and B, and the DNA primase large and small subunits. Subunit B binds to subunit A.,
组织表达
Cervix epithelium,Epithelium,Lung,
信号通路
Purine metabolism;Pyrimidine metabolism;DNA replication;
功能
domain:The N-terminal 240 amino acids are sufficient to mediate complex formation.,function:May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery.,PTM:Phosphorylated in a cell cycle-dependent manner, in G2/M phase.,similarity:Belongs to the DNA polymerase alpha subunit B family.,subunit:DNA polymerase alpha:primase is a four subunit enzyme complex, which is assembled throughout the cell cycle, and consists of the two DNA polymerase subunits A and B, and the DNA primase large and small subunits. Subunit B binds to subunit A.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
