产品名称
5NTC Rabbit Polyclonal Antibody
基因名称
NT5C2 NT5B NT5CP PNT5
蛋白名称
Cytosolic purine 5'-nucleotidase (EC 3.1.3.5) (Cytosolic 5'-nucleotidase II)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P49902
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P49902/entry
Mouse Swissprot No.
Q3V1L4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3V1L4
免疫原
Synthesized peptide derived from part region of human protein
特异性
5NTC Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides. [provided by RefSeq, Oct 2011],
细胞定位
Cytoplasm, cytosol .
信号通路
Purine metabolism;Pyrimidine metabolism;Nicotinate and nicotinamide metabolism;
功能
catalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,cofactor:Binds 1 magnesium ion per subunit.,disease:Aberration of this enzyme may be related to the urate production in hyperuricemia and gout.,enzyme regulation:Allosterically activated by various compounds, including ATP.,function:May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides.,similarity:Belongs to the 5'(3')-deoxyribonucleotidase family.,subunit:Homotetramer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
