产品名称
CYTF Rabbit Polyclonal Antibody
蛋白名称
Cystatin-F (Cystatin-7) (Cystatin-like metastasis-associated protein) (CMAP) (Leukocystatin)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O76096
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O76096/entry
Mouse Swissprot No.
O89098
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O89098
免疫原
Synthesized peptide derived from part region of human protein
特异性
CYTF Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. This gene encodes a glycosylated cysteine protease inhibitor with a putative role in immune regulation through inhibition of a unique target in the hematopoietic system. Expression of the protein has been observed in various human cancer cell lines established from malignant tumors. [provided by RefSeq, Jul 2008],
组织表达
Primarily expressed in peripheral blood cells and spleen.
细胞定位
Secreted . Cytoplasm .
功能
function:Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system.,similarity:Belongs to the cystatin family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Primarily expressed in peripheral blood cells and spleen.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
