产品名称
GRP4 Rabbit Polyclonal Antibody
蛋白名称
RAS guanyl-releasing protein 4
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/115727
Human Swissprot No.
Q8TDF6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8TDF6/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/233046
Mouse Swissprot No.
Q8BTM9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BTM9
Rat Gene Link
https://www.uniprot.org/uniprot/233046
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q8R5I4
免疫原
Synthesized peptide derived from human GRP4 AA range: 487-537
特异性
This antibody detects endogenous levels of human GRP4
宿主
Polyclonal, Rabbit,IgG
组织表达
Expressed by mast cells and their progenitors (at protein level). Specifically expressed in mononuclear leukocytes. Highly expressed in myeloid cells compared to lymphoid cells. Also detected in heart, skeletal muscle, spleen, liver, placenta and lung. Not detected in brain. Isoform 1 is the major isoform in normal individuals. Isoform 2 is more significantly expressed in a patient with asthma. Isoform 3 is more significantly expressed in a patient with asthma and a mastocytosis patient.
细胞定位
Cytoplasm. Cell membrane. Recruited to membranes upon activation by DAG.
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
