产品名称
SKAP Rabbit Polyclonal Antibody
基因名称
SKAP C15orf23 TRAF4AF1 HSD11
蛋白名称
Small kinetochore-associated protein (SKAP) (Kinetochore-localized astrin-binding protein) (Kinastrin) (TRAF4-associated factor 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/90417
Human Swissprot No.
Q9Y448
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y448/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/51944
Mouse Swissprot No.
Q9D9Z1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D9Z1
Rat Gene Link
https://www.uniprot.org/uniprot/51944
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q6AXN6
免疫原
Synthesized peptide derived from human SKAP AA range: 34-84
特异性
This antibody detects endogenous levels of human SKAP
宿主
Polyclonal, Rabbit,IgG
组织表达
Widely expressed, including in skin.
细胞定位
Nucleus . Chromosome, centromere, kinetochore . Cytoplasm, cytoskeleton, spindle pole . Cytoplasm, cytoskeleton, microtubule organizing center . Colocalizes with microtubules around centrosomes in prophase and with the mitotic spindle at prometaphase and metaphase. From late prometaphase to anaphase, is highly concentrated on kinetochores. Located at the kinetochore-microtubule interface. The astrin (SPAG5)-kinastrin (SKAP) complex localizes to the microtubule plus ends (PubMed:23035123). .
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.