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CLD22 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PN0603
产品名称
CLD22 Rabbit Polyclonal Antibody
类别
常规抗体
基因名称
CLDN22
蛋白名称
Claudin-22
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Gene ID
53842
Human Swissprot No.
Q8N7P3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8N7P3/entry
Mouse Swissprot No.
Q9D7U6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9D7U6
免疫原
Synthesized peptide derived from part region of human protein AA range: 139-189
特异性
CLD22 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
预测分子量
24kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and overlaps the 3' UTR of the WWC2 gene (GeneID: 80014) on the opposite strand. [provided by RefSeq, Aug 2010],
组织表达
Trachea,
细胞定位
Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein .
信号通路
Cell adhesion molecules (CAMs);Tight junction;Leukocyte transendothelial migration;
功能
function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.,similarity:Belongs to the claudin family.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°over night

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