产品名称
LC7L3 Rabbit Polyclonal Antibody
基因名称
LUC7L3 CREAP1 CROP O48
蛋白名称
Luc7-like protein 3 (Cisplatin resistance-associated-overexpressed protein) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18) (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O95232
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O95232/entry
Mouse Swissprot No.
Q5SUF2
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q5SUF2
免疫原
Synthesized peptide derived from part region of human protein
特异性
LC7L3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein with an N-terminal half that contains cysteine/histidine motifs and leucine zipper-like repeats, and the C-terminal half is rich in arginine and glutamate residues (RE domain) and arginine and serine residues (RS domain). This protein localizes with a speckled pattern in the nucleus, and could be involved in the formation of splicesome via the RE and RS domains. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2009],
组织表达
Widely expressed. Highest levels in heart, brain, pancreas, thymus, ovary, small intestine and peripheral blood leukocytes, as well as cerebellum, putamen and pituitary gland. Lowest levels in lung, liver and kidney. Also expressed in fetal tissues, including brain, heart, kidney, thymus and lung.
细胞定位
Nucleus speckle . The subnuclear localization is affected by cisplatin.
功能
RNA processing,?mRNA processing,?apoptosis,?cell death,?RNA splicing,?programmed cell death,?mRNA metabolic process,?death,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.