产品名称
NINL Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/22981
Human Swissprot No.
Q9Y2I6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y2I6/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/78177
Mouse Swissprot No.
Q6ZQ12
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6ZQ12
Rat Gene Link
https://www.uniprot.org/uniprot/78177
免疫原
Synthesized peptide derived from human NINL AA range: 1098-1148
特异性
This antibody detects endogenous levels of human NINL
宿主
Polyclonal, Rabbit,IgG
组织表达
Expressed in KYSE-150 esophageal carcinoma, HeLa cervical carcinoma and U2OS osteosarcoma cells. Expression is regulated in a cell cycle-dependent manner and peaks during G2/M phase (at protein level). Expressed in fetal heart, skeletal muscle, liver, lung and cochlea, and in adult brain, testis, kidney and retina.
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm . In interphase cells, NINL is transported to the centrosomes by the dynein-dynactin motor complex (PubMed:16254247). During centrosome maturation, PLK1 directly phosphorylates NINL resulting in its release into the cytoplasm (PubMed:16254247).
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
