产品名称
PDCD6 Rabbit Polyclonal Antibody
蛋白名称
Programmed cell death protein 6 (Apoptosis-linked gene 2 protein) (Probable calcium-binding protein ALG-2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/10016
Human Swissprot No.
O75340
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O75340/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/18570
Mouse Swissprot No.
P12815
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P12815
Rat Gene Link
https://www.uniprot.org/uniprot/18570
免疫原
Synthesized peptide derived from human PDCD6 AA range: 98-148
特异性
This antibody detects endogenous levels of human PDCD6
宿主
Polyclonal, Rabbit,IgG
细胞定位
Endoplasmic reticulum membrane ; Peripheral membrane protein . Cytoplasmic vesicle, COPII-coated vesicle membrane . Cytoplasm . Nucleus . Endosome . Interaction with RBM22 induces relocalization from the cytoplasm to the nucleus (PubMed:17045351). Translocated from the cytoplasm to the nucleus after heat shock cell treatment. Accumulates in cytoplasmic vesicle-like organelles after heat shock treatment, which may represent stress granules (PubMed:21122810). In response to calcium increase, relocates from cytoplasm to COPII vesicle coat (PubMed:27716508). Localizes to endoplasmic reticulum exit site (ERES) (PubMed:27813252). .
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.