产品名称
CEP63 Rabbit Polyclonal Antibody
蛋白名称
Centrosomal protein of 63 kDa (Cep63)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q96MT8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96MT8/entry
Mouse Swissprot No.
Q3UPP8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3UPP8
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q4KLY0
免疫原
Synthesized peptide derived from part region of human protein
特异性
CEP63 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein with six coiled-coil domains. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. Several alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],
组织表达
Pancreas,Placenta,Teratocarcinoma,
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite . Colocalizes with CDK5RAP2, CEP152 and WDR62 in a discrete ring around the proximal end of the parental centriole. At this site, a cohesive structure is predicted to engage parental centrioles and procentrioles. .
功能
cell cycle checkpoint,?DNA damage checkpoint,?M phase of mitotic cell cycle,?microtubule cytoskeleton organization,mitotic cell cycle,?M phase,?nuclear division,?response to DNA damage stimulus,?cytoskeleton organization,?microtubule-based process,?cell cycle,?spindle organization,?mitosis,?intracellular signaling cascade,?cell cycle process,?cell cycle phase,?DNA integrity checkpoint,?cellular response to stress,?DNA damage response, signal transduction,?organelle fission,?spindle assembly,?cell division,?regulation of cell cycle,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
