产品名称
DEDD2 Rabbit Polyclonal Antibody
基因名称
DEDD2 FLAME3 PSEC0004
蛋白名称
DNA-binding death effector domain-containing protein 2 (DED-containing protein FLAME-3) (FADD-like anti-apoptotic molecule 3)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/162989
Human Swissprot No.
Q8WXF8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8WXF8/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/67379
Mouse Swissprot No.
Q8QZV0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8QZV0
Rat Gene Link
https://www.uniprot.org/uniprot/67379
免疫原
Synthesized peptide derived from human DEDD2 AA range: 226-276
特异性
This antibody detects endogenous levels of human DEDD2
宿主
Polyclonal, Rabbit,IgG
组织表达
Expressed in most tissues. High levels were found in liver, kidney, heart, ovary, spleen, testes, skeletal muscle and peripheral blood leukocytes. Expression was absent or low in colon and small intestine. Expression is relatively high in the tumor cell lines chronic myologenous leukemia K-562 and the colorectal adenocarcinoma SW480. Expression is moderate in the cervical carcinoma HeLa, the Burkitt's lymphoma Raji, the lung carcinoma A-549, and the melanoma G-361. In contrast, two leukemia cell lines, HL-60 (promyelocytic leukemia) and MOLT-4 (lymphoblastic leukemia), show relatively low levels.
细胞定位
Nucleus, nucleolus . Nuclear, accumulated in subnuclear structures resembling nucleoli.
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
