产品名称
ACAP2 Rabbit Polyclonal Antibody
基因名称
ACAP2 CENTB2 KIAA0041
蛋白名称
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (Centaurin-beta-2) (Cnt-b2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q15057
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q15057/entry
Mouse Swissprot No.
Q6ZQK5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q6ZQK5
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q5FVC7
免疫原
Synthesized peptide derived from part region of human protein
特异性
ACAP2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
enzyme regulation:GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.,function:GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 Arf-GAP domain.,similarity:Contains 1 BAR domain.,similarity:Contains 1 PH domain.,similarity:Contains 3 ANK repeats.,tissue specificity:Widely expressed. Highest level in lung.,
组织表达
Widely expressed. Highest level in lung.
细胞定位
Endosome membrane ; Peripheral membrane protein .
功能
enzyme regulation:GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.,function:GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 Arf-GAP domain.,similarity:Contains 1 BAR domain.,similarity:Contains 1 PH domain.,similarity:Contains 3 ANK repeats.,tissue specificity:Widely expressed. Highest level in lung.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
