产品名称
GRP2 Rabbit Polyclonal Antibody
蛋白名称
RAS guanyl-releasing protein 2 (Calcium and DAG-regulated guanine nucleotide exchange factor I) (CalDAG-GEFI) (Cdc25-like protein) (hCDC25L) (F25B3.3 kinase-like protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/10235
Human Swissprot No.
Q7LDG7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q7LDG7/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/19395
Mouse Swissprot No.
Q9QUG9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9QUG9
Rat Gene Link
https://www.uniprot.org/uniprot/19395
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P0C643
免疫原
Synthesized peptide derived from human GRP2 AA range: 492-542
特异性
This antibody detects endogenous levels of human GRP2
宿主
Polyclonal, Rabbit,IgG
组织表达
Detected in platelets, neutrophils and T lymphocytes (at protein level). Expressed in brain where it is enriched in the striatum. Also expressed in the hematopoietic system. Detected in heart, brain, lung, placenta, liver, skeletal muscle and kidney.
细胞定位
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Cell junction, synapse, synaptosome . Cell projection, ruffle membrane ; Peripheral membrane protein . Found both in the cytosol and associated with membranes. Isoform 2 mainly localizes to the cell membrane. Enriched at juxtamembrane areas and membrane ruffles through association with F-actin. Localizes to the cell bodies and axons of striatal neurons (By similarity). .
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
