产品名称
BORG5 Rabbit Polyclonal Antibody
基因名称
CDC42EP1 BORG5 CEP1 MSE55
蛋白名称
Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q00587
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q00587/entry
Mouse Swissprot No.
Q91W92
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q91W92
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941A1A5P0
免疫原
Synthesized peptide derived from part region of human protein
特异性
BORG5 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin cytoskeleton reorganization at the plasma membrane. This protein is secreted and is primarily found in bone marrow. [provided by RefSeq, Jul 2008],
组织表达
Endothelial and bone marrow stromal cells.
细胞定位
Endomembrane system ; Peripheral membrane protein . Cytoplasm, cytoskeleton .
功能
domain:The CRIB domain mediates interaction with CDC42.,function:Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts.,similarity:Belongs to the BORG/CEP family.,similarity:Contains 1 CRIB domain.,subunit:Interacts with RHOQ and CDC42, in a GTP-dependent manner.,tissue specificity:Endothelial and bone marrow stromal cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
