产品名称
HOOK1 Rabbit Polyclonal Antibody
蛋白名称
Protein Hook homolog 1 (h-hook1) (hHK1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/51361
Human Swissprot No.
Q9UJC3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UJC3/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/77963
Mouse Swissprot No.
Q8BIL5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BIL5
Rat Gene Link
https://www.uniprot.org/uniprot/77963
免疫原
Synthesized peptide derived from human HOOK1 AA range: 201-251
特异性
This antibody detects endogenous levels of human HOOK1
宿主
Polyclonal, Rabbit,IgG
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton . Localizes to punctate cytoplasmic foci which do not appear to overlap with early or late endosomes, the endoplasmic reticulum, multivesicular bodies (MVBs), lysosomes, or mitochondria (By similarity). Often found in close association with microtubules (By similarity). Does not associate with the Golgi complex. During spermiogenesis, it localizes to the manchette in spermatids from steps 8-10. It is also present between the microtubule manchette and the nucleus. During manchette elongation, it is preferentially localized to the nuclear ring of the manchette, whereas the strong localization to the manchette decreases. In more mature spermatids, while the manchette migrates posteriorly, it localizes to punctuates spots. At later stages of spermatid differentiation, the punctuate expression pattern is found at both the attachment site and the proximal end of the elongated manchette. In contrast, it is not present in mature spermatozoa (By similarity). .
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
