产品名称
CHAC1 Rabbit Polyclonal Antibody
蛋白名称
Cation transport regulator-like protein 1 (Blocks Notch protein) (Botch)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9BUX1
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9BUX1/entry
Mouse Swissprot No.
Q8R3J5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8R3J5
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941B3STU3
免疫原
Synthesized peptide derived from part region of human protein
特异性
CHAC1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the gamma-glutamylcyclotransferase family of proteins. The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. This protein may also play a role in the unfolded protein response, and in regulation of glutathione levels and oxidative balance in the cell. Elevated expression of this gene may indicate increased risk of cancer recurrence among breast and ovarian cancer patients. [provided by RefSeq, Sep 2016],
细胞定位
Cytoplasm, cytosol . Golgi apparatus, trans-Golgi network .
功能
similarity:Belongs to the chaC family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.