产品名称
PTGDS Rabbit Polyclonal Antibody
蛋白名称
Prostaglandin-H2 D-isomerase (EC 5.3.99.2) (Beta-trace protein) (Cerebrin-28) (Glutathione-independent PGD synthase) (Lipocalin-type prostaglandin-D synthase) (Prostaglandin-D2 synthase) (PGD2 synthase) (PGDS) (PGDS2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/5730
Human Swissprot No.
P41222
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P41222/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/19215
Mouse Swissprot No.
O09114
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/O09114
Rat Gene Link
https://www.uniprot.org/uniprot/19215
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P22057
免疫原
Synthesized peptide derived from human PTGDS AA range: 115-165
特异性
This antibody detects endogenous levels of human PTGDS
宿主
Polyclonal, Rabbit,IgG
组织表达
Abundant in the brain and CNS, where it is expressed in tissues of the blood-brain barrier and secreted into the cerebro-spinal fluid. Abundantly expressed in the heart. In the male reproductive system, it is expressed in the testis, epididymis and prostate, and is secreted into the seminal fluid. Expressed in the eye and secreted into the aqueous humor. Lower levels detected in various tissue fluids such as serum, normal urine, ascitic fluid and tear fluid. Also found in a number of other organs including ovary, fimbriae of the fallopian tubes, kidney, leukocytes.
细胞定位
Rough endoplasmic reticulum . Nucleus membrane . Golgi apparatus . Cytoplasm, perinuclear region . Secreted . Detected on rough endoplasmic reticulum of arachnoid and menigioma cells. Localized to the nuclear envelope, Golgi apparatus, secretory vesicles and spherical cytoplasmic structures in arachnoid trabecular cells, and to circular cytoplasmic structures in meningeal macrophages and perivascular microglial cells. In oligodendrocytes, localized to the rough endoplasmic reticulum and nuclear envelope. In retinal pigment epithelial cells, localized to distinct cytoplasmic domains including the perinuclear region. Also secreted.
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
