产品名称
CBPB1 Rabbit Polyclonal Antibody
蛋白名称
Carboxypeptidase B (EC 3.4.17.2) (Pancreas-specific protein) (PASP)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P15086
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P15086/entry
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P19223
免疫原
Synthesized peptide derived from part region of human protein
特异性
CBPB1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma. [provided by RefSeq, Jul 2008],
细胞定位
Secreted . Zymogen granule lumen .
功能
catalytic activity:Preferential release of a C-terminal lysine or arginine amino acid.,cofactor:Binds 1 zinc ion per subunit.,similarity:Belongs to the peptidase M14 family.,tissue specificity:Pancreas.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.