产品名称
CAH11 Rabbit Polyclonal Antibody
基因名称
CA11 CARP2 UNQ211/PRO237
蛋白名称
Carbonic anhydrase-related protein 11 (CA-RP XI) (CA-XI) (CARP XI) (Carbonic anhydrase-related protein 2) (CA-RP II) (CARP-2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O75493
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O75493/entry
Mouse Swissprot No.
O70354
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O70354
免疫原
Synthesized peptide derived from part region of human protein
特异性
CAH11 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system. [provided by RefSeq, Jul 2008],
组织表达
Expressed abundantly in the brain with moderate expression also present in spinal cord and thyroid.
功能
function:Does not have a catalytic activity.,similarity:Belongs to the alpha-carbonic anhydrase family.,tissue specificity:Expressed abundantly in the brain with moderate expression also present in spinal cord and thyroid.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
