产品名称
MACF1 Rabbit Polyclonal Antibody
基因名称
MACF1 ABP620 ACF7 KIAA0465 KIAA1251
蛋白名称
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/23499
Human Swissprot No.
Q9UPN3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UPN3/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/11426
Mouse Swissprot No.
Q9QXZ0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9QXZ0
Rat Gene Link
https://www.uniprot.org/uniprot/11426
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/D3ZHV2
免疫原
Synthesized peptide derived from human MACF1 AA range: 5623-5673
特异性
This antibody detects endogenous levels of human MACF1
宿主
Polyclonal, Rabbit,IgG
组织表达
Isoform 2: Ubiquitously expressed. Isoform 1: Expressed in cell lines NCI-H460, A-549 and HaCaT. Isoform 4: Expressed in heart, lung, pituitary and placenta, not found in brain, kidney, liver, pancreas or skeletal muscle.
细胞定位
[Isoform 2]: Cytoplasm, cytoskeleton . Cytoplasm . Golgi apparatus . Cell membrane . Cell projection, ruffle membrane . The phosphorylated form is found in the cytoplasm while the non-phosphorylated form associates with the microtubules (By similarity). Localizes to the tips of microtubules (PubMed:27693509). Associated with the minus-end of microtubules via interaction with CAMSAP3 (PubMed:27693509). APC controls its localization to the cell membrane which is critical for its function in microtubule stabilization (PubMed:20937854). .; [Isoform 1]: Cytoplasm . Golgi apparatus . Localizes to the tips of microtubules. .
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
