产品名称
CNN3 Rabbit Polyclonal Antibody
蛋白名称
Calponin-3 (Calponin, acidic isoform)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q15417
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q15417/entry
Mouse Swissprot No.
Q9DAW9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9DAW9
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P37397
免疫原
Synthesized peptide derived from part region of human protein
特异性
CNN3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein with a markedly acidic C terminus; the basic N-terminus is highly homologous to the N-terminus of a related gene, CNN1. Members of the CNN gene family all contain similar tandemly repeated motifs. This encoded protein is associated with the cytoskeleton but is not involved in contraction. [provided by RefSeq, Jul 2008],
组织表达
Expressed in both non-smooth muscle tissues as well as smooth muscle tissues.
细胞定位
cytoplasm,cell-cell adherens junction,focal adhesion,postsynaptic density,actin cytoskeleton,neuronal cell body,dendritic spine,
功能
function:Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.,similarity:Belongs to the calponin family.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 3 calponin-like repeats.,tissue specificity:Expressed in both non-smooth muscle tissues as well as smooth muscle tissues.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
