产品名称
CAN13 Rabbit Polyclonal Antibody
蛋白名称
Calpain-13 (EC 3.4.22.-) (Calcium-activated neutral proteinase 13) (CANP 13)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q6MZZ7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6MZZ7/entry
Mouse Swissprot No.
Q3UW68
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3UW68
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q5BK10
免疫原
Synthesized peptide derived from part region of human protein
特异性
CAN13 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes a member of the calpain large subunit family. [provided by RefSeq, Jun 2012],
组织表达
Weakly expressed in lung and testis. Weakly or not expressed in other tissues.
细胞定位
intracellular,cytoplasm,
功能
caution:It is unlikely that this protein binds calcium as none of the 2 EF-hand domains seem to contain a canonical calcium-binding site.,function:Probable non-lysosomal thiol-protease.,similarity:Belongs to the peptidase C2 family.,similarity:Contains 1 calpain catalytic domain.,similarity:Contains 2 EF-hand domains.,tissue specificity:Weakly expressed in lung and testis. Weakly or not expressed in other tissues.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
