产品名称
Tubulin β (Acetyl Lys379) Rabbit Polyclonal Antibody
蛋白名称
Tubulin β (Acetyl Lys379)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/7280
Human Swissprot No.
Q13885/Q9BVA1/Q13509/P04350/P68371/P07437/Q9BUF5/
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q13885/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/22151
Mouse Swissprot No.
Q7TMM9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q7TMM9
Rat Gene Link
https://www.uniprot.org/uniprot/498736
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P85108
免疫原
Synthesized peptide derived from human Tubulin β (Acetyl Lys379)
特异性
This antibody detects endogenous levels of Human,Mouse,Rat Tubulin β (Acetyl Lys379)
稀释度
WB 1:1000-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Microtubules, key participants in processes such as mitosis and intracellular transport, are composed of heterodimers of alpha- and beta-tubulins. The protein encoded by this gene is a beta-tubulin. Defects in this gene are associated with complex cortical dysplasia with other brain malformations-5. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2015],
组织表达
High expression in brain, where it represents 30% of all beta-tubulins.
细胞定位
Cytoplasm, cytoskeleton .
功能
function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.