产品名称
KLF13 (Acetyl Lys166) Rabbit Polyclonal Antibody
别名
Krueppel-like factor 13 (Basic transcription element-binding protein 3;BTE-binding protein 3;Novel Sp1-like zinc finger transcription factor 1;RANTES factor of late activated T-lymphocytes 1;RFLAT-1;Transcription factor BTEB3;Transcription factor NSLP1)
蛋白名称
KLF13 (Acetyl Lys166)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/51621
Human Swissprot No.
Q9Y2Y9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y2Y9/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/50794
Mouse Swissprot No.
Q9JJZ6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JJZ6
免疫原
Synthesized peptide derived from human KLF13 (Acetyl Lys166)
特异性
This antibody detects endogenous levels of Human,Mouse KLF13 (Acetyl Lys166)
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).[supplied by OMIM, Mar 2008],
功能
domain:The Ala/Pro-rich domain may contain discrete activation and repression subdomains and also can mediate protein-protein interactions.,function:Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES expression in T-cells.,PTM:Phosphorylated.,similarity:Belongs to the Sp1 C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,tissue specificity:Ubiquitous.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
