产品名称
HMG-17 (Acetyl Lys31) Rabbit Polyclonal Antibody
别名
Non-histone chromosomal protein HMG-17 (High mobility group nucleosome-binding domain-containing protein 2)
蛋白名称
HMG-17 (Acetyl Lys31)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/3151
Human Swissprot No.
P05204
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P05204/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/100503799
Mouse Swissprot No.
P09602
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P09602
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P18437
免疫原
Synthesized peptide derived from human HMG-17 (Acetyl Lys31)
特异性
This antibody detects endogenous levels of Human,Mouse,Rat HMG-17 (Acetyl Lys31)
稀释度
WB 1:1000-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
high mobility group nucleosomal binding domain 2(HMGN2) Homo sapiens The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi. [provided by RefSeq, Oct 2014],
细胞定位
Nucleus . Cytoplasm . Cytoplasmic enrichment upon phosphorylation.
功能
function:Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in an unique chromatin conformation.,mass spectrometry: PubMed:10739259,PTM:Phosphorylation favors cytoplasmic localization.,similarity:Belongs to the HMGN family.,subcellular location:Cytoplasmic enrichment upon phosphorylation.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
