BD-PK0103

C/EBP β (Acetyl Lys265) Rabbit Polyclonal Antibody

CCAAT/enhancer-binding protein beta (C/EBP beta;Liver activator protein;Nuclear factor NF-IL6;Transcription factor 5;TCF-5)

常规抗体

CEBPB LAP TCF5 PP9092

C/EBP β (Acetyl Lys265)

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

1051

https://www.uniprot.org/uniprot/1051

P17676

https://www.uniprot.org/uniprotkb/P17676/entry

12608

https://www.uniprot.org/uniprot/12608

P28033

https://www.uniprot.org/uniprotkb/P28033

24253

https://www.uniprot.org/uniprot/24253

P21272

https://www.uniprot.org/uniprotkb/P21272

Synthesized peptide derived from human C/EBP β (Acetyl Lys265)

This antibody detects endogenous levels of Human,Mouse,Rat C/EBP β (Acetyl Lys265)

WB 1:1000-2000 ELISA 1:5000-20000

40kD

-20°C/1 year

Polyclonal, Rabbit,IgG

function:Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses. Specifically binds to an IL-1 response element in the IL-6 gene. NF-IL6 also binds to regulatory regions of several acute-phase and cytokines genes. It probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'.,PTM:Sumoylated by polymeric chains of SUMO2 or SUMO3.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. C/EBP subfamily.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer and can form stable heterodimers with C/EBP alpha, delta and gamma. Interacts with TRIM28 and PTGES2.,tissue specificity:Expressed at low levels in the lung, kidney and spleen.,

Expressed at low levels in the lung, kidney and spleen.

Nucleus . Cytoplasm . Translocates to the nucleus when phosphorylated at Ser-288. In T-cells when sumoylated drawn to pericentric heterochromatin thereby allowing proliferation (By similarity). .

in utero embryonic development,?regulation of cytokine production,?placenta development,?embryonic placenta development,?acute inflammatory response,?transcription,?transcription, DNA-dependent,?regulation of transcription, DNA-dependent,?regulation of transcription from RNA polymerase II promoter,?transcription from RNA polymerase II promoter,?anti-apoptosis,?induction of apoptosis,?defense response,?acute-phase response,?inflammatory response,immune response,?response to wounding,?embryonic development ending in birth or egg hatching,?positive regulation of biosynthetic process,?positive regulation of macromolecule biosynthetic process,?positive regulation of macromolecule metabolic process,?positive regulation of gene expression,?regulation of cell death,?positive regulation of cell death,?induction of programmed cell death,?neuron differentiation,?positive regulation of cellular biosynthetic process,?regulation of interleukin-6 production,?RNA biosynthetic process,?regulation of cytokine biosynthetic process,regulation of apoptosis,?chordate embryonic development,?positive regulation of apoptosis,?negative regulation of apoptosis,?regulation of programmed cell death,?positive regulation of programmed cell death,?negative regulation of programmed cell death,?regulation of interleukin-6 biosynthetic process,?fat cell differentiation,?regulation of transcription,?positive regulation of transcription, DNA-dependent,?positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process,?positive regulation of transcription,?positive regulation of transcription from RNA polymerase II promoter,?embryonic organ development,?positive regulation of nitrogen compound metabolic process,?regulation of RNA metabolic process,?positive regulation of RNA metabolic process,?negative regulation of cell death,

现货

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.