产品名称
PPGB (20k, Cleaved-Met327) Rabbit Polyclonal Antibody
别名
Lysosomal protective protein (EC 3.4.16.5;Carboxypeptidase C;Carboxypeptidase L;Cathepsin A;Protective protein cathepsin A;PPCA;Protective protein for beta-galactosidase) [Cleaved into: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain]
蛋白名称
PPGB (20k, Cleaved-Met327)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/5476
Human Swissprot No.
P10619
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P10619/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/19025
Mouse Swissprot No.
P16675
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P16675
免疫原
Synthesized peptide derived from human PPGB (20k, Cleaved-Met327)
特异性
This antibody detects endogenous levels of Human,Mouse PPGB (20k, Cleaved-Met327, protein was cleaved amino acid sequence between 326-327 )
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
catalytic activity:Release of a C-terminal amino acid with broad specificity.,disease:Defects in CTSA are the cause of galactosialidosis [MIM:256540]. It is an autosomal recessive disease.,function:Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.,similarity:Belongs to the peptidase S10 family.,subunit:Heterodimer of a 32 kDa chain and a 20 kDa chain; disulfide-linked.,
功能
proteolysis,?intracellular protein transport,?protein localization,?protein transport,?cellular protein localization,establishment of protein localization,?intracellular transport,?cellular macromolecule localization,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
