产品名称
Kallikrein-6 (Cleaved-Leu22) Rabbit Polyclonal Antibody
别名
Kallikrein-6 (EC 3.4.21.-;Neurosin;Protease M;SP59;Serine protease 18;Serine protease 9;Zyme)
蛋白名称
Kallikrein-6 (Cleaved-Leu22)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/5653
Human Swissprot No.
Q92876
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q92876/entry
免疫原
Synthesized peptide derived from human Kallikrein-6 (Cleaved-Leu22)
特异性
This antibody detects endogenous levels of Human Kallikrein-6 (Cleaved-Leu22, protein was cleaved amino acid sequence between 21-22 )
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
组织表达
In fluids, highest levels found in milk of lactating women followed by cerebrospinal fluid, nipple aspirate fluid and breast cyst fluid. Also found in serum, seminal plasma and some amniotic fluids and breast tumor cytosolic extracts. Not detected in urine. At the tissue level, highest concentrations found in glandular tissues such as salivary glands followed by lung, colon, fallopian tube, placenta, breast, pituitary and kidney. Not detected in skin, spleen, bone, thyroid, heart, ureter, liver, muscle, endometrium, testis, pancreas, seminal vesicle, ovary, adrenals and prostate. In brain, detected in gray matter neurons (at protein level). Colocalizes with pathological inclusions such as Lewy bodies and glial cytoplasmic inclusions. Overexpressed in primary breast tumors but not expressed in metastatic tumors.
细胞定位
Secreted. Nucleus, nucleolus. Cytoplasm. Mitochondrion. Microsome. In brain, detected in the nucleus of glial cells and in the nucleus and cytoplasm of neurons. Detected in the mitochondrial and microsomal fractions of HEK-293 cells and released into the cytoplasm following cell stress.
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
