产品名称
EFNA1 (Cleaved-Ser182) Rabbit Polyclonal Antibody
别名
Ephrin-A1 (EPH-related receptor tyrosine kinase ligand 1;LERK-1;Immediate early response protein B61;Tumor necrosis factor alpha-induced protein 4;TNF alpha-induced protein 4) [Cleaved into: Ephrin-A1, secreted form]
基因名称
EFNA1 EPLG1 LERK1 TNFAIP4
蛋白名称
EFNA1 (Cleaved-Ser182)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/1942
Human Swissprot No.
P20827
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P20827/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/13636
Mouse Swissprot No.
P52793
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P52793
Rat Gene Link
https://www.uniprot.org/uniprot/94268
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P97553
免疫原
Synthesized peptide derived from human EFNA1 (Cleaved-Ser182)
特异性
This antibody detects endogenous levels of Human,Mouse,Rat EFNA1 (Cleaved-Ser182, protein was cleaved amino acid sequence between 182-183 )
稀释度
WB 1:1000-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
induction:By TNF-alpha and interleukin-1 beta.,similarity:Belongs to the ephrin family.,subunit:Binds to the receptor tyrosine kinases EPHA2, EPHA4, EPHA5, EPHA6 and EPHA7. Also binds with low affinity to EPHA1.,
组织表达
Brain. Down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells (at protein level).
细胞定位
Cell membrane ; Lipid-anchor, GPI-anchor .; [Ephrin-A1, secreted form]: Secreted .
功能
MAPKKK cascade,?activation of MAPK activity,?protein amino acid phosphorylation,?phosphorus metabolic process,phosphate metabolic process,?cell surface receptor linked signal transduction,?enzyme linked receptor protein signaling pathway,?transmembrane receptor protein tyrosine kinase signaling pathway,?intracellular signaling cascade,protein kinase cascade,?cell-cell signaling,?regulation of cell morphogenesis involved in differentiation,?regulation of neuron projection development,?phosphorylation,?regulation of phosphate metabolic process,?regulation of cell morphogenesis,?neuron differentiation,?regulation of cell projection organization,?positive regulation of kinase activity,regulation of phosphorylation,?positive regulation of catalytic activity,?regulation of MAP kinase activity,?positive regulation of MAP kinase activity,?regulation of kinase activity,?positive regulation of molecular function,?regulation of neuron differentiation,?regulation of protein kinase activity,?positive regulation of protein kinase activity,?ephrin receptor signaling pathway,?regulation of neurogenesis,?regulation of axonogenesis,?regulation of phosphorus metabolic process,?regulation of transferase activity,?positive regulation of transferase activity,?regulation of nervous system development,?regulation of cell development,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
