BD-PB3763

SULT2B1(13Q2)Mouse Monoclonal Antibody

Sulfotransferase family cytosolic 2B member 1, ST2B1, Sulfotransferase 2B1, 2.8.2.2, Alcohol sulfotransferase, Hydroxysteroid sulfotransferase 2, SULT2B1, HSST2

常规抗体

WB

Human

O00204

This antibody is generated from a mouse immunized with a reconbinant protein from human.

WB~~1:2000

41kDa

IgG1,κ

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol. Plays a role in epidermal cholesterol metabolism and in the regulation of epidermal proliferation and differentiation (PubMed:28575648).

Expressed in the stratum granulosum-stratum corneum junction in the skin (at protein level) (PubMed:28575648). Expressed highly in placenta, prostate and trachea and lower expression in the small intestine and lung (PubMed:9799594)

Cytoplasm, cytosol. Microsome. Nucleus. Note=Phosphorylation of Ser-348 is required for translocation to the nucleus

现货