产品名称
CANB1 Rabbit Polyclonal Antibody
蛋白名称
Calcineurin subunit B type 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P63098
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P63098/entry
Mouse Swissprot No.
Q63810
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q63810
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P63100
免疫原
Synthesized peptide derived from part region of human protein
特异性
CANB1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.,miscellaneous:This protein has four functional calcium-binding sites.,similarity:Belongs to the calcineurin regulatory subunit family.,similarity:Contains 4 EF-hand domains.,subunit:Composed of a catalytic subunit (A) and a regulatory subunit (B).,
组织表达
Blood,Fetal brain cortex,
细胞定位
Cytoplasm, cytosol . Cell membrane . Cell membrane, sarcolemma . Cell membrane ; Lipid-anchor . Translocates from the cytosol to the sarcolemma in a CIB1-dependent manner during cardiomyocyte hypertrophy. .
信号通路
MAPK_ERK_Growth;MAPK_G_Protein;Calcium;Oocyte meiosis;Apoptosis_Inhibition;Apoptosis_Mitochondrial;Apoptosis_Overview;WNT;WNT-T CELLAxon guidance;VEGF;Natural killer cell mediated cytotoxicity;T_Cell_Receptor;B_Cell_Antigen;Long-term potentiation;Alzheime
功能
function:Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.,miscellaneous:This protein has four functional calcium-binding sites.,similarity:Belongs to the calcineurin regulatory subunit family.,similarity:Contains 4 EF-hand domains.,subunit:Composed of a catalytic subunit (A) and a regulatory subunit (B).,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
