BD-PB3697-REG3G(2T4)Mouse Monoclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

REG3G(2T4)Mouse Monoclonal Antibody

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产品基本信息

产品货号

BD-PB3697

产品名称

REG3G(2T4)Mouse Monoclonal Antibody

别名

Regenerating islet-derived protein 3-gamma, REG-3-gamma, Pancreatitis-associated protein 1B, PAP-1B, Pancreatitis-associated protein IB, PAP IB, Regenerating islet-derived protein III-gamma, REG III, Reg III-gamma, Regenerating islet-derived protein 3-gamma 16.5 kDa form, Regenerating islet-derived protein 3-gamma 15 kDa form, REG3G, PAP1B

类别

常规抗体

推荐应用

反应种属

Human

Human Swissprot No.

Q6UW15

特异性

This REG3G antibody is generated from a mouse immunized with a recombinant protein of human REG3G.

稀释度

IHC-P~~1:100~500;WB~~1:1000

预测分子量

19kDa

同种型

IgG1,k

背景介绍

Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury.

组织表达

Predominantly expressed in pancreas, where it may be restricted to exocrine pancreas. Moderate expression levels in testis and weak in heart, kidney and placenta

细胞定位

Secreted. Cytoplasm.

期货

现货

BD-PB3697 staining REG3G in human pancreas tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde and blocked with 3% BSA for 0. 5 hour at room temperature; antigen retrieval was by heat mediation with a citrate buffer (pH6). Samples were incubated with primary antibody (1/25) for 1 hours at 37°C. A undiluted biotinylated goat polyvalent antibody was used as the secondary antibody.

Anti-REG3G Antibody at 1:1000 dilution + Human pancreas lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 19 kDa Blocking/Dilution buffer: 5% NFDM/TBST.