产品名称
POPD1 Rabbit Polyclonal Antibody
蛋白名称
Blood vessel epicardial substance (hBVES) (Popeye domain-containing protein 1) (Popeye protein 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8NE79
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8NE79/entry
Mouse Swissprot No.
Q9ES83
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9ES83
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q3BCU4
免疫原
Synthesized peptide derived from part region of human protein
特异性
POPD1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
blood vessel epicardial substance(BVES) Homo sapiens This gene encodes a member of the POP family of proteins containing three putative transmembrane domains. This gene is expressed in cardiac and skeletal muscle and may play an important role in development of these tissues. The mouse ortholog may be involved in the regeneration of adult skeletal muscle and may act as a cell adhesion molecule in coronary vasculogenesis. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010],
组织表达
Expressed in epithelial cells (at protein level). Expressed in fetal and adult heart and skeletal muscle.
细胞定位
Lateral cell membrane . Cell junction, tight junction . Membrane ; Multi-pass membrane protein . Cell membrane, sarcolemma . Membrane, caveola . Colocalizes with VAMP3 at the cell-cell contact in cardiac and skeletal muscle (By similarity). Its movement from the cytoplasm to membrane is an early event occurring concurrently with cell-cell contact. Colocalizes in epithelial cells with OCLN and TJP1 in an apical-lateral position within the z axis. Detected at cell-cell contact but never observed at the free surface of epithelial cells. .
功能
function:May play an important role in heart development.,similarity:Belongs to the popeye family.,tissue specificity:Expressed in fetal and adult heart and skeletal muscle.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
