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SH3BP5 Rabbit Polyclonal Antibody (N-Term)

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产品基本信息

产品货号
BD-PB3663
产品名称
SH3BP5 Rabbit Polyclonal Antibody (N-Term)
别名
SH3 domain-binding protein 5, SH3BP-5, SH3 domain-binding protein that preferentially associates with BTK, SH3BP5, SAB
类别
常规抗体
推荐应用
WB
反应种属
Human, Mouse
Human Swissprot No.
O60239
特异性
This SH3BP5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 63-97 amino acids from human SH3BP5.
稀释度
WB~~1:2000
预测分子量
50kDa
同种型
Rabbit Ig
背景介绍
Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.
组织表达
Highly expressed in testis and ovaries. It is also expressed in a variety of tissues including spleen, lymph node, thymus, bone marrow, fetal liver, colon, small intestine and prostate
细胞定位
Cytoplasmic vesicle membrane; Peripheral membrane protein. Mitochondrion. Note=Colocalizes with RAB11A on cytoplasmic vesicle membranes.
期货
现货

Anti-SH3BP5 Antibody (N-Term) at 1:2000 dilution + human ovary lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 50 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

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