BD-PB3643-TIGIT Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

TIGIT Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PB3643

产品名称

TIGIT Rabbit Polyclonal Antibody

别名

T-cell immunoreceptor with Ig and ITIM domains, V-set and immunoglobulin domain-containing protein 9, V-set and transmembrane domain-containing protein 3, TIGIT, VSIG9, VSTM3

类别

常规抗体

推荐应用

反应种属

Human, Mouse

Human Swissprot No.

Q495A1

特异性

This TIGIT antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 12-142 amino acids from human TIGIT.

稀释度

WB~~1:2000

预测分子量

26kDa

同种型

Rabbit Ig

背景介绍

Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.

组织表达

Expressed at low levels on peripheral memory and regulatory CD4+ T-cells and NK cells and is up-regulated following activation of these cells (at protein level)

细胞定位

Cell membrane; Single-pass type I membrane protein

期货

现货

All lanes : Anti-TIGIT Antibody at 1:2000 dilution Lane 1: EL4 whole cell lysate Lane 2: human fetal thymus lysate Lane 3: human spleen lysate Lane 4: HUT78 whole cell lysate Lane 5: Jurkat whole cell lysate Lane 6: MOLT-4 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 26 kDa Blocking/Dilution buffer: 5% NFDM/TBST.