BD-PB3616-FEM1B Rabbit Polyclonal Antibody (C-Term)-现货抗体产品库武汉枢密脑科学技术有限公司

FEM1B Rabbit Polyclonal Antibody (C-Term)

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产品基本信息

产品货号

BD-PB3616

产品名称

FEM1B Rabbit Polyclonal Antibody (C-Term)

别名

Protein fem-1 homolog B, FEM1b, FEM1-beta, Fem-1-like death receptor-binding protein alpha, Fem-1-like in apoptotic pathway protein alpha, F1A-alpha, FEM1B, F1AA, KIAA0396

类别

常规抗体

推荐应用

反应种属

Human, Rat, Mouse

Human Swissprot No.

Q9UK73

特异性

This FEM1B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 547-579 amino acids from human FEM1B.

稀释度

WB~~1:2000

预测分子量

70kDa

同种型

Rabbit Ig

背景介绍

Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.

组织表达

Widely expressed (PubMed:10542291). Highly expressed in testis (PubMed:10542291). Weakly expressed in other tissues (PubMed:10542291).

细胞定位

Cytoplasm. Nucleus Note=In the nucleus, the protein level increased slightly after camptothecin (CPT) treatment (PubMed:19330022). Associated with chromatin (PubMed:19330022).

期货

现货

All lanes : Anti-FEM1B Antibody (C-Term) at 1:2000 dilution Lane 1: 293T/17 whole cell lysate Lane 2: mouse testis lysate Lane 3: MCF-7 whole cell lysate Lane 4: rat testis lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 70 kDa Blocking/Dilution buffer: 5% NFDM/TBST.