BD-PB3572-NAA10 Rabbit Polyclonal Antibody (Center)-现货抗体产品库武汉枢密脑科学技术有限公司

NAA10 Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号

BD-PB3572

产品名称

NAA10 Rabbit Polyclonal Antibody (Center)

别名

N-alpha-acetyltransferase 10, 2.3.1.-, 2.3.1.88, N-terminal acetyltransferase complex ARD1 subunit homolog A, NatA catalytic subunit Naa10, NAA10, ARD1, ARD1A, TE2

类别

常规抗体

推荐应用

反应种属

Human, Mouse

Human Swissprot No.

P41227

特异性

This NAA10 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 135-167 amino acids from the Central region of human NAA10.

稀释度

IF~~1:25;WB~~1:2000

预测分子量

26kDa

同种型

Rabbit Ig

背景介绍

Catalytic subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity. The NAT activity may be important for vascular, hematopoietic and neuronal growth and development. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration. Acetylates, and stabilizes TSC2, thereby repressing mTOR activity and suppressing cancer development.

组织表达

Ubiquitous..

细胞定位

Cytoplasm. Nucleus. Note=Also present in the free cytosolic and cytoskeleton-bound polysomes.

期货

现货

Immunofluorescent analysis of 4% paraformaldehyde-fixed, 0.1% Triton X-100 permeabilized U-2 OS (human osteosarcoma cell line) cells labeling NAA10 with BD-PB3572 at 1/25 dilution, followed by Dylight® 488-conjugated goat anti-rabbit IgG secondary antibody at 1/200 dilution (green). Immunofluorescence image showing cytoplasm and weak nucleus staining on U-2 OS cell line. The nuclear counter stain is DAPI (blue).

All lanes : Anti-NAA10 Antibody (Center) at 1:2000 dilution Lane 1: SK-BR-3 whole cell lysate Lane 2: Hela whole cell lysate Lane 3: HCT116 whole cell lysate Lane 4: MCF-7 whole cell lysate Lane 5: HL-60 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 26 kDa Blocking/Dilution buffer: 5% NFDM/TBST.