BD-PN0493

IRK8 Rabbit Polyclonal Antibody

常规抗体

KCNJ8

ATP-sensitive inward rectifier potassium channel 8 (Inward rectifier K(+) channel Kir6.1) (Potassium channel, inwardly rectifying subfamily J member 8) (uKATP-1)

WB

Human,Rat,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

3764

Q15842

https://www.uniprot.org/uniprotkb/Q15842/entry

P97794

http://www.uniprot.org/uniprot/P97794

Q63664

http://www.uniprot.org/uniprot/O54941Q63664

Synthesized peptide derived from human protein . at AA range: 50-130

IRK8 Polyclonal Antibody detects endogenous levels of protein.

WB 1:500-2000 ELISA 1:5000-20000

46kD

-20°C/1 year

Polyclonal, Rabbit,IgG

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. Defects in this gene may be a cause of J-wave syndromes and sudden infant death syndrome (SIDS). [provided by RefSeq, May 2012],

Predominantly detected in fetal and adult heart.

Membrane; Multi-pass membrane protein .

function:This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium.,similarity:Belongs to the inward rectifier-type potassium channel family.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.