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TNRC6A Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号
BD-PB3530
产品名称
TNRC6A Rabbit Polyclonal Antibody (Center)
别名
Trinucleotide repeat-containing gene 6A protein, CAG repeat protein 26, EMSY interactor protein, GW182 autoantigen, Protein GW1, Glycine-tryptophan protein of 182 kDa, TNRC6A, CAGH26, KIAA1460, TNRC6
类别
常规抗体
推荐应用
WB
反应种属
Human, Mouse
Human Swissprot No.
Q8NDV7
特异性
This TNRC6A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 855-885 amino acids from the Central region of human TNRC6A.
稀释度
WB~~1:1000-1:2000
预测分子量
210kDa
同种型
Rabbit Ig
背景介绍
Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent repression of translation and for siRNA- dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes.
组织表达
Ubiquitous.
细胞定位
Cytoplasm, P-body. Note=Mammalian P-bodies are also known as GW bodies (GWBs).
期货
现货

All lanes : Anti-TNRC6A Antibody (Center) at 1:1000-1:2000 dilution Lane 1: human skeletal muscle lysate Lane 2: Hela whole cell lysate Lane 3: MCF-7 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 210 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

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