BD-PB3488-ZKSCAN3 Rabbit Polyclonal Antibody (N-Term)-现货抗体产品库武汉枢密脑科学技术有限公司

ZKSCAN3 Rabbit Polyclonal Antibody (N-Term)

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产品基本信息

产品货号

BD-PB3488

产品名称

ZKSCAN3 Rabbit Polyclonal Antibody (N-Term)

别名

Zinc finger protein with KRAB and SCAN domains 3, Zinc finger and SCAN domain-containing protein 13, Zinc finger protein 306, Zinc finger protein 309, Zinc finger protein 47 homolog, Zf47, Zfp-47, ZKSCAN3, ZFP47, ZNF306, ZNF309, ZSCAN13

类别

常规抗体

推荐应用

反应种属

Human, Mouse

Human Swissprot No.

Q9BRR0

特异性

This ZKSCAN3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 100-130 amino acids from human ZKSCAN3.

稀释度

WB~~1:2000

预测分子量

61kDa

同种型

Rabbit Ig

背景介绍

Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.

细胞定位

Nucleus. Cytoplasm. Note=Mainly localizes in the nucleus. Under starvation conditions translocates to the cytoplasm, allowing expression of target genes involved in autophagy and lysosome biogenesis/function

期货

现货

Anti-ZKSCAN3 Antibody (N-Term) at 1:2000 dilution + human brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 61 kDa Blocking/Dilution buffer: 5% NFDM/TBST.