产品名称
DDX18 Rabbit Polyclonal Antibody
蛋白名称
ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9NVP1
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NVP1/entry
Mouse Swissprot No.
Q8K363
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K363
免疫原
Synthesized peptide derived from human protein . at AA range: 590-670
特异性
DDX18 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it is activated by Myc protein. [provided by RefSeq, Jul 2008],
组织表达
Brain,Placenta,Platelet,Tongue,
细胞定位
Nucleus, nucleolus . Chromosome .
功能
function:Probable RNA-dependent helicase.,similarity:Belongs to the DEAD box helicase family.,similarity:Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
