BD-PB3453-RAP2A Rabbit Polyclonal Antibody (C-Term)-现货抗体产品库武汉枢密脑科学技术有限公司

RAP2A Rabbit Polyclonal Antibody (C-Term)

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产品基本信息

产品货号

BD-PB3453

产品名称

RAP2A Rabbit Polyclonal Antibody (C-Term)

别名

Ras-related protein Rap-2a, RbBP-30, RAP2A

类别

常规抗体

推荐应用

反应种属

Human

Human Swissprot No.

P10114

特异性

This RAP2A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 124-159 amino acids from human RAP2A.

稀释度

WB~~1:2000

预测分子量

21kDa

同种型

Rabbit Ig

背景介绍

Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.

细胞定位

Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Midbody. Note=May also localize to the Golgi (PubMed:7962206) and the gelatinase-containing granules of neutrophils (PubMed:8391995). Colocalizes with RASGEF1B to midbody at telophase (PubMed:23894443).

期货

现货

Anti-RAP2A Antibody (C-Term) at 1:2000 dilution + A431 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 21 kDa Blocking/Dilution buffer: 5% NFDM/TBST.