BD-PB3394-NCSTN Rabbit Polyclonal Antibody (N-Term)-现货抗体产品库武汉枢密脑科学技术有限公司

NCSTN Rabbit Polyclonal Antibody (N-Term)

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产品基本信息

产品货号

BD-PB3394

产品名称

NCSTN Rabbit Polyclonal Antibody (N-Term)

别名

Nicastrin, NCSTN, KIAA0253

类别

常规抗体

推荐应用

反应种属

Human, Rat, Mouse

Human Swissprot No.

Q92542

特异性

This NCSTN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 99-133 amino acids from human NCSTN.

稀释度

WB~~1:2000

预测分子量

78kDa

同种型

Rabbit Ig

背景介绍

Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta- amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.

组织表达

Detected in brain (at protein level) (PubMed:10993067). Widely expressed (PubMed:11396676)

细胞定位

Membrane; Single-pass type I membrane protein. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV

期货

现货

All lanes : Anti-NCSTN Antibody (N-Term) at 1:8000 dilution Lane 1: HL-60 whole cell lysates Lane 2: Hela whole cell lysates Lane 3: C6 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 78 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

All lanes : Anti-NCSTN Antibody (N-Term) at 1:2000 dilution Lane 1: Jurkat whole cell lysates Lane 2: A431 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 78 kDa Blocking/Dilution buffer: 5% NFDM/TBST.