BD-PB3333

(Mouse) Bmi1 Rabbit Polyclonal Antibody (C-term)

Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, Bmi1, Bmi-1, Pcgf4

常规抗体

WB

Human, Rat, Mouse

P25916

This mouse Bmi1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 235-268 amino acids from the C-terminal region of mouse Bmi1.

WB~~1:2000

37kDa

Rabbit Ig

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2 (By similarity).

Detected in most organs with high expression levels in thymus, heart, brain and testis

Nucleus {ECO:0000250|UniProtKB:P35226}. Cytoplasm {ECO:0000250|UniProtKB:P35226}

现货