BD-PB3314

(Mouse) Hopx Rabbit Polyclonal Antibody (Center)

Homeodomain-only protein, Homeobox-only protein, Odd homeobox protein 1, mOB1, Hopx, Hod, Hop, Ob1

常规抗体

WB

Human, Rat, Mouse

Q8R1H0

This Mouse Hopx antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 22-54 amino acids from the Central region of Mouse Hopx.

WB~~1:1000

8kDa

Rabbit Ig

Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy.

Expressed in the embryonic and adult heart and in the adult brain, liver, lung, skeletal muscle, intestine and spleen Throughout embryonic and postnatal development, it is expressed in the myocardium.

Nucleus. Cytoplasm. Note=According to PubMed:14516659 it is cytoplasmic.

现货