BD-PN0471

ABCAA Rabbit Polyclonal Antibody

常规抗体

ABCA10

ATP-binding cassette sub-family A member 10

WB

Human,Rat,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

10349

Q8WWZ4

https://www.uniprot.org/uniprotkb/Q8WWZ4/entry

Synthesized peptide derived from human protein . at AA range: 1100-1180

ABCAA Polyclonal Antibody detects endogenous levels of protein.

WB 1:500-2000 ELISA 1:5000-20000

169kD

-20°C/1 year

Polyclonal, Rabbit,IgG

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. [provided by RefSeq, Jul 2008],

Widely expressed. Highly expressed in skeletal muscle, heart, brain and gastrointestinal tract.

Membrane ; Multi-pass membrane protein .

ABC transporters;

function:Probable transporter which may play a role in macrophage lipid homeostasis.,induction:Down-regulated by cholesterol loading of macrophages.,similarity:Belongs to the ABC transporter family. ABCA subfamily.,similarity:Contains 2 ABC transporter domains.,tissue specificity:Widely expressed. Highly expressed in skeletal muscle, heart, brain and gastrointestinal tract.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.