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PTK7 Rabbit Polyclonal Antibody (N-Term)

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产品基本信息

产品货号
BD-PB3293
产品名称
PTK7 Rabbit Polyclonal Antibody (N-Term)
别名
Inactive tyrosine-protein kinase 7, Colon carcinoma kinase 4, CCK-4, Protein-tyrosine kinase 7, Pseudo tyrosine kinase receptor 7, Tyrosine-protein kinase-like 7, PTK7, CCK4
类别
常规抗体
推荐应用
WB
反应种属
Human, Mouse
Human Swissprot No.
Q13308
特异性
This PTK7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 331-363 amino acids from the human region of human PTK7.
稀释度
WB~~1:2000
预测分子量
118kDa
同种型
Rabbit Ig
背景介绍
Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
组织表达
Highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. But not expressed in colon
细胞定位
Membrane; Single- pass type I membrane protein. Cell junction. Note=Colocalizes with MMP14 at cell junctions. Also localizes at the leading edge of migrating cells
期货
现货

All lanes : Anti-PTK7 Antibody (N-Term) at 1:2000 dilution Lane 1: Hela whole cell lysates Lane 2: C2C12 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 118 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

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