BD-PB3277

(Mouse) Med15 Rabbit Polyclonal Antibody (C-term)

Mediator of RNA polymerase II transcription subunit 15, Mediator complex subunit 15, Positive cofactor 2 glutamine/Q-rich-associated protein, PC2 glutamine/Q-rich-associated protein, mPcqap, Med15, Pcqap

常规抗体

WB

Human, Rat, Mouse

Q924H2

This Mouse Med15 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 743-779 amino acids from the C-terminal region of Mouse Med15.

WB~~1:2000

87kDa

Rabbit Ig

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway (By similarity).

Cytoplasm. Nucleus.

现货