BD-PB3273

PCGF6 Rabbit Polyclonal Antibody (Center)

Polycomb group RING finger protein 6, Mel18 and Bmi1-like RING finger, RING finger protein 134, PCGF6, MBLR, RNF134

常规抗体

WB

Human, Rat, Mouse

Q9BYE7

This PCGF6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 215-249 amino acids from the Central region of human PCGF6.

WB~~1:2000

39kDa

Rabbit Ig

Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Ubiquitous.

Nucleus

现货