BD-PB3211

ASGR2 Rabbit Polyclonal Antibody (N-term)

Asialoglycoprotein receptor 2, ASGP-R 2, ASGPR 2, C-type lectin domain family 4 member H2, Hepatic lectin H2, HL-2, ASGR2, CLEC4H2

常规抗体

WB

Human

P07307

This ASGR2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 21-54 amino acids from the N-terminal region of human ASGR2.

WB~~1:1000

35kDa

Rabbit Ig

Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.

Expressed exclusively in hepatic parenchymal cells.

Membrane; Single-pass type II membrane protein.

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